2018 AANS Annual Scientific Meeting-502. Single-Neuronal Basis for Interactive Social Behavior in a Primate Model

502. Single-Neuronal Basis for Interactive Social Behavior in a Primate Model

Video Transcription

Video Summary

The video presentation is titled "Single Neuronal Basis for Interactive Social Behavior in a Primate Model" and is given by Amy Wang. The presenter discusses the importance of understanding the neuronal basis for interactive social behavior in order to develop targeted therapies for neurocognitive disorders such as autism spectrum disorder, depression, and schizophrenia. The study uses rhesus macaques as a primate model to study social behavior. The presenter explains a structured social task involving reward allocation among the monkeys. They found that the monkeys showed preferences for specific individuals and engaged in strategic behavior, such as reciprocating rewards. Neuronal recordings in the dorsal anterior cingulate revealed three main response types: self encoding, general other encoding, and specific other encoding. These findings contribute to the understanding of social behavior at the neural level and may have implications for the development of therapies. The discussant, Joseph Nemat, commends the innovative and thoughtful design of the experiment and discusses the importance of studying social interactions in primate research. He also mentions the potential therapeutic applications of deep brain stimulation and expresses interest in the ongoing research in this field.

Asset Caption

Amy Julia Wang

Keywords

neurocognitive disorders

rhesus macaques

structured social task

neuronal recordings

deep brain stimulation