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2018 AANS Annual Scientific Meeting
514. Multi-agent vs. Single-agent Intraventricular ...
514. Multi-agent vs. Single-agent Intraventricular Chemotherapy for Patients with Neoplastic Meningitis (NM): Changing the Reputation of a Fearsome Disease
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Video Summary
In the video, Samer Zamar, a second-year resident at Penn State Neurosurgery, discusses multi-agent versus single-agent interventricular chemotherapy for patients with neoplastic meningitis. Neoplastic meningitis is considered an end-stage disease with a poor survival rate. The use of radiation and systemic chemotherapy has shown some benefits in controlling the primary disease, but intrathecal (IT) chemotherapy has been the standard of care. Zamar compares overall survival between patients receiving multi-agent IT chemotherapy and those receiving single-agent IT chemotherapy. The results show significant survival benefits in patients receiving multi-agent chemotherapy, particularly for patients with solid tumors and lymphoma. The study suggests that further research in a randomized controlled trial is needed to validate these findings.
Asset Caption
Samer Zammar, MD
Keywords
video
Samer Zamar
multi-agent versus single-agent interventricular chemotherapy
neoplastic meningitis
overall survival
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