2018 AANS Annual Scientific Meeting-516. Alterations to Information Transmission in the Brain following Spinal Cord Injury: A Resting-State Functional Connectivity Analysis

516. Alterations to Information Transmission in the Brain following Spinal Cord Injury: A Resting-State Functional Connectivity Analysis

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Video Transcription

Video Summary

Mayank Kaushal presents research findings on changes seen in brain networks using resting state fMRI following spinal cord injury. He discusses the epidemiology of spinal cord injuries, including the prevalence and lifetime costs. He explains the primary and secondary mechanisms of injury and the anatomical and imaging evidence of neural damage. Kaushal introduces the use of resting state fMRI to study changes in neuroplasticity and multiple brain networks. He describes the theory behind resting fMRI and the recruitment criteria and imaging parameters used in the study. The results show reduced connectivity matrices in spinal cord injury patients compared to controls, indicating compromised segregation potential of the brain. Resting state fMRI may be used to study neurosurgically relevant populations and potentially develop non-invasive biomarkers for prognosis and functional recovery measurement. No credits are mentioned.

Asset Caption

Mayank Kaushal

Keywords

brain networks

resting state fMRI

spinal cord injury

neuroplasticity

connectivity matrices