2018 AANS Annual Scientific Meeting-517. Kyphoplasty Intraoperative Radiation Therapy: A New Treatment Paradigm for Spinal Metastasis

517. Kyphoplasty Intraoperative Radiation Therapy: A New Treatment Paradigm for Spinal Metastasis – Phase I/II Clinical Trial

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Video Summary

In this video, Dr. Shashank Gandhi from Northwell Health discusses kyphoplasty intraoperative radiation therapy as a new treatment for spinal metastatic disease. Metastatic disease in the spinal column is common among cancer patients and often requires surgery followed by radiation. However, there are limitations to traditional radiation treatment, including delayed pain improvement and vertebral fractures. Kyphoplasty intraoperative radiation combines radiation and kyphoplasty in one procedure, allowing for immediate sterilization and stabilization of the vertebral body. The procedure uses accelerator electrons to deliver focused radiation while protecting the spinal cord. A Phase I-II clinical trial showed improvement in pain and quality of life, with comparable local control to standard radiation. The procedure is considered safe and can be done in an ambulatory treatment center.

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Shashank Gandhi, MD

Keywords

kyphoplasty intraoperative radiation therapy

spinal metastatic disease

cancer patients

vertebral fractures

accelerator electrons