2018 AANS Annual Scientific Meeting-519. Mesenchymal Stem Cell-Seeded High-Density Collagen Gel For Annular Repair: In Vivo Sheep Study

519. Mesenchymal Stem Cell-Seeded High-Density Collagen Gel For Annular Repair: In Vivo Sheep Study

Video Transcription

Video Summary

Dr. Ibrahim Hussain presents his research on biologic approaches for annular repair in a video. He discusses the development of a high-density collagen gel that is cross-linked with riboflavin and blue light, and its efficacy in plugging the annular defect and preventing disc degeneration. Dr. Hussain explains how the addition of mosaicom stem cells to the collagen gel improves its efficacy, as shown in various radiographic and histologic studies. He concludes that the treatment demonstrates improved outcomes compared to the acellular formulation and discusses future plans for further research and device development. Dr. Hussain acknowledges collaborators and his team.

Asset Caption

Ibrahim Hussain, MD

Keywords

annular repair

collagen gel

disc degeneration

stem cells

device development