2018 AANS Annual Scientific Meeting-528. Chiari Malformation Clusters Describe Differing Presence of Concurrent Anomalies based on Chiari Type

528. Chiari Malformation Clusters Describe Differing Presence of Concurrent Anomalies based on Chiari Type

Video Transcription

Video Summary

Dr. Janjua discusses the presence of concurrent anomalies based on different types of Chiari malformations. Chiari malformations are structural defects resulting from congenital hyperplasia of the posterior fossa. The study primarily focuses on four types of Chiari malformations, and the objective is to determine the nationwide incidence of each type and their associated anomalies. The study uses data from the Nationwide Inpatient Sample from 2002 to 2012, utilizing ICD-9 codes for classification. The results show that 44% of Chiari patients have at least one concurrent anomaly, with the most common being neuro-tube defects, congenital hydrocephalus, and ASD defects. Other associated conditions include scoliosis, seringomyelia, telecoresyndrome, and Ehlers-Danlos syndrome. Chiari types 3 and 4 are particularly associated with neuro-tube defects and hindbrain hypoplasia.

Asset Caption

Muhammad Burhan Ud Din Janjua, MD

Keywords

Chiari malformations

concurrent anomalies

structural defects

posterior fossa

nationwide incidence