2018 AANS Annual Scientific Meeting-547. Analysis of Thermal Damage Estimates for the Prediction of Mesiotemporal Laser Ablation Zones

547. Analysis of Thermal Damage Estimates for the Prediction of Mesiotemporal Laser Ablation Zones

Video Transcription

Video Summary

In this video, Dr. Jermakowicz discusses the analysis of thermal damage estimates for the prediction of mesiotemporal laser ablation zone in the treatment of mesiotemporal epilepsy. Laser interstitial thermal therapy (LITT) has become a minimally invasive treatment option due to advances in MRI thermometry. TDE maps, which estimate cell damage, are used by surgeons for intraoperative decision-making. The study aimed to evaluate the impact of patient and procedure-specific variables on tissue ablation dynamics and compared TDE maps to immediate and delayed ablations. Results showed that T2 signal and axial laser angle were associated with slower ablation, and TDE maps correlated closely with immediate ablation zones but were more variable with delayed ablation zones. The study suggests that incorporating preoperative imaging data may improve predictions of LITT effects. The video concludes with a discussion among the presenters about tissue contraction and the challenges of accurately analyzing post-operative imaging.

Asset Caption

Walter Jermakowicz, MD, PhD

Keywords

thermal damage estimates

mesiotemporal laser ablation zone

LITT

TDE maps

preoperative imaging data