2018 AANS Annual Scientific Meeting-554. Risk-Adjusted Overall Survival for Pediatric High Grade Astrocytomas by Location and Treatment in a National Cohort

554. Risk-Adjusted Overall Survival for Pediatric High Grade Astrocytomas by Location and Treatment in a National Cohort

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Video Transcription

Video Summary

In this video, Dr. Igor Oskolou discusses the risk-adjusted overall survival rates for pediatric high-grade astrocytomas based on their location and treatment. The study used the National Cancer Database and included over 1,600 cases of newly diagnosed pediatric high-grade astrocytomas. The results showed that hemispheric tumors had the best overall survival, while brainstem gliomas had the worst. Gross total resection and chemotherapy were associated with improved survival, especially in hemispheric tumors. The study highlights the importance of understanding the molecular pathways and characteristics of different tumor locations to improve treatment strategies.

Asset Caption

J. Bryan Iorgulescu, MD

Keywords

Dr. Igor Oskolou

pediatric high-grade astrocytomas

overall survival rates

tumor location

treatment strategies