Next, we'll go through a series of seven rapid-fire abstracts. I would like to ask the subsequent or next presenter to already come up during each presentation so we can proceed without delay. And the first one is from Dr. Foreman on phases score applied to a prospective cohort of aneurysmal subarachnoid hemorrhage patients. Good afternoon. As said, my name is Paul Foreman. I'm from the University of Alabama, Birmingham. We'll be discussing the phases score as it applies to aneurysmal subarachnoid hemorrhage patients. No relevant disclosures. Starting with a little epidemiology of aneurysms, this was a large systematic review and meta-analysis conducted on just under 100,000 patients that found a prevalence of right at 3% in the general population. Of course, what we're all concerned about is these aneurysms rupturing. This is ISUIA published in 2003 in Lancet. Found right just under a 1% rupture risk per year. This was heavily influenced by aneurysm size as well as location. This 1% number was subsequently found by UCAS as well as the Juvela study. Putting this all together, the authors of the phases score combined individual patient data from six prospective cohort studies and assembled it to construct a predictive risk model, estimating five-year rupture risk. The data points that were identified were the population, presence or absence of hypertension, age, the site of the aneurysm, previous subarachnoid hemorrhage as well as aneurysm location. With greater phases risk scores, the risk of aneurysm rupture increases. We wanted to see what this would look like if we applied it to a prospective group of aneurysmal subarachnoid hemorrhage patients collected at three universities in the United States from 2012 to 2015. We had 149 patients. The majority were young women with small aneurysms. Looking at the phases variables, you can see that nearly 90% of our patients were under the age of 70. They almost all had small aneurysms that were located either the ACA or the PCOM. Putting these numbers together, you can see that the majority of our patients were presenting with phases scores of four to five with an estimated five-year rupture risk of right around 1%. Interestingly, in multivariable analysis, the phases score was also found to be predictive of functional outcome at last follow-up. In conclusion, the majority of our aneurysmal subarachnoid hemorrhage patients presented with low phases scores. These were, the vast majority were young women with small anterior circulation aneurysms, specifically at the ACA and posterior communicating artery. The rupture risk is multifactorial, and the phases score was independently associated with functional outcome. I'd like to thank our contributors at University of Alabama, Birmingham, Inova, as well as Geisinger. Thank you.

phases score

aneurysmal subarachnoid hemorrhage

rupture risk

predictive risk model

functional outcome