2018 AANS Annual Scientific Meeting-575. Effects of combined neural stem cell therapy and treadmill training on functional recovery, cyst formation and astrogliosis after cervical spinal cord injury

575. Effects of combined neural stem cell therapy and treadmill training on functional recovery, cyst formation and astrogliosis after cervical spinal cord injury

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Video Summary

In this video, Alexander Yudin discusses the effects of combined neural stem cell therapy and treadmill training on functional recovery after cervical spinal cord injury (SCI). Yudin explains that transportation of neural precursor cells (NPCs) after SCI has shown to benefit neural regeneration, but functional recovery is still limited due to post-traumatic changes. Treadmill training has been shown to improve these effects. Yudin conducted an experiment involving NPC transplantation and treadmill training in rats with SCI. The results showed that the combined treatment led to increased NPC survival, NPC differentiation into oligodendrocytes, and improved functional recovery. Yudin suggests that this approach could enhance stem cell therapy in the future.

Asset Caption

Alexander Younsi, MD (Germany)

Keywords

Alexander Yudin

neural stem cell therapy

treadmill training

functional recovery

cervical spinal cord injury