2018 AANS Annual Scientific Meeting-595. Seizure Outcomes and Cognitive Deficits Following Laser Interstitial Thermal Ablation in Mesial Temporal Epilepsy Patients

595. Seizure Outcomes and Cognitive Deficits Following Laser Interstitial Thermal Ablation in Mesial Temporal Epilepsy Patients

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Video Summary

Dr. Cristian Donos from the University of Texas discusses the seizure outcomes and cognitive deficits following laser ablation therapy in patients with mesial temporal lobe epilepsy (MTLE). The talk includes a case series of 43 patients over five years, with seizure-free rates of 80% at six months and 65% at 20 months. The ablation volumes and cognitive outcomes were also assessed, with the average percentage of ablation in the amygdala hippocampus around 75%. The cognitive outcomes showed no changes in naming and fluency tests, but some deficits in memory tests. The study concludes that laser ablation therapy is comparable to traditional open surgeries, and carefully selected MTLE patients can achieve similar surgical outcomes as those with MTS. The talk also mentions the importance of SEG guidance in improving outcomes.

Asset Caption

Cristian Donos

Keywords

seizure outcomes

cognitive deficits

laser ablation therapy

mesial temporal lobe epilepsy

case series