2018 AANS Annual Scientific Meeting-612. Mathematical model of perineural tumor spread

612. Mathematical model of perineural tumor spread - pilot study on 2 cases

Video Transcription

Video Summary

In this video, Dr. Stefan Capek, a second-year resident at UVA, presents a pilot study on a mathematical model of perineural tumor spread. The study focuses on neoplastic lumbosacral plexopathy caused by the spread of tumor cells along autonomic nerves to the lumbosacral plexus. The slow process of perineural spread makes it difficult to diagnose and treat. To overcome the lack of data on the initial history and progression of this condition, the researchers reviewed a series of perineural spread cases and created a model to predict tumor progression. The study involved two subjects, and the simulation results correlated well with the actual MRIs. While the study has limitations, it serves as a first step in developing a treatment response monitoring tool for tumor treatment. Dr. Capek gives credit to Dr. Spinner and Josh Jacobs for their contribution to the project.

Asset Caption

Stepan Capek, MD

Keywords

perineural tumor spread

neoplastic lumbosacral plexopathy

tumor cells

autonomic nerves

lumbosacral plexus