2018 AANS Annual Scientific Meeting-619. A closed loop deep brain stimulation system for essential tremor

619. A closed loop deep brain stimulation system for essential tremor

Video Transcription

Video Summary

In this video, Dr. Andrew Koh discusses the use of a closed loop deep brain stimulation (DBS) system for treating essential tremor, the most common movement disorder. The current DBS system used for essential tremor is effective but lacks responsiveness to patient behavior and is considered a static therapy. The goal of this research is to develop a closed loop system that responds to patient physiology. The system uses wearable sensors, inertial sensors, and surface electromyography (EMG) to detect movement and tremor. The Activa PC Plus S system by Medtronic is used for the closed loop trial, which monitors brain signals and delivers DBS on demand. The study found that using the EMG-triggered stimulation resulted in better tremor control and significant power reduction. The closed loop system was also evaluated using electrocorticography data, and it showed promising results in detecting motor cortex activity and providing more responsive stimulation. The video concludes by mentioning the potential benefits of this system, such as extended battery life and improved patient experience. The research team acknowledges that further optimization and exploration of different brain regions are needed.

Asset Caption

Andrew Lin Ko, MD

Keywords

closed loop deep brain stimulation

essential tremor

wearable sensors

surface electromyography

Activa PC Plus S system