2018 AANS Annual Scientific Meeting-625. Distinct cortical regions mediate improvements in individual motor symptoms after subthalamic nucleus deep brain stimulation in Parkinson’s disease

625. Distinct cortical regions mediate improvements in individual motor symptoms after subthalamic nucleus deep brain stimulation in Parkinson’s disease

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Video Summary

Dr. Vibhor Krishna discusses his research on the neuroimaging correlates of effective stimulation in patients undergoing deep brain stimulation (DBS) for Parkinson's disease. He focuses on studying the distinct cortical regions that mediate improvements in individual motor symptoms after DBS. Through probabilistic tractography, Dr. Krishna identifies unique cortical areas associated with each symptom improvement, such as rigidity, bradykinesia, and tremor. He also explores the implications of this research for shaping the electrical field with directional leads and improving stimulation titration efficiency. While the study has limitations, such as the lack of functional studies, it provides valuable insights for patient care.

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Vibhor Krishna, MD

Keywords

neuroimaging correlates

deep brain stimulation

Parkinson's disease

cortical regions

motor symptoms