2018 AANS Annual Scientific Meeting-627. Effect of Platelet Dysfunction on Outcomes in Traumatic Brain Injury

627. Effect of Platelet Dysfunction on Outcomes in Traumatic Brain Injury

Video Transcription

Video Summary

In this video, Andrew Gaiot, a second-year medical student at the University of Missouri, discusses the effect of platelet dysfunction on outcomes in traumatic brain injury. Coagulopathy is a common complication in TBI and is associated with poor outcomes. Many TBI patients have prior use of platelet-inhibiting medications, making them at high risk of platelet dysfunction. The speaker discusses the use of thromboelastography (TAG) to evaluate coagulopathy and platelet function. The goals of the project were to evaluate the incidence and severity of TAG abnormalities in TBI patients, identify factors contributing to platelet dysfunction, and assess whether transfusing platelets improves outcomes. The study found that platelet dysfunction was associated with the severity of TBI, but transfusing platelets did not significantly improve outcomes. Further research is needed to understand platelet dysfunction better and determine appropriate treatment.

Asset Caption

Andrew R. Guillotte

Keywords

platelet dysfunction

traumatic brain injury

coagulopathy

thromboelastography

transfusing platelets