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Catalog
2018 AANS Annual Scientific Meeting
639. Intraoperative Assessment of Meningioma Proli ...
639. Intraoperative Assessment of Meningioma Proliferative Potential Revealed Intratumoral Heterogeneity and Its Relevance to Biological Characteristics
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Video Transcription
Video Summary
Dr. Soichi Oya from Saitama Medical University in Japan discusses the use of intraoperative flow cytometry as a substitute for the MIB1 labeling index in meningioma surgeries. He explains that while maximum safe resection is important, the biological features of tumors influence recurrence rates and overall prognosis more significantly. Intraoperative flow cytometry allows for the evaluation of DNA content and cell count in tumor specimens, providing information about the proliferation index. Dr. Oya presents data showing a correlation between the proliferation index and the MIB1 labeling index, as well as tumor growth rate and intratumoral heterogeneity. He suggests that this method can help guide surgical strategies and aid in the selection of patients for upfront radiosurgery. The limitations and future perspectives of this technique are also discussed. (Transcript credit: Dr. Soichi Oya)
Asset Caption
Soichi Oya, MD, IFAANS (Japan)
Keywords
intraoperative flow cytometry
MIB1 labeling index
meningioma surgeries
tumor specimens
proliferation index
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