2018 AANS Annual Scientific Meeting-721. Non-surgical Treatment to Prevent Post-hemorrhagic Hydrocephalus of Prematurity

721. Non-surgical Treatment to Prevent Post-hemorrhagic Hydrocephalus of Prematurity

Video Transcription

Video Summary

In this video, Fatou Conteh, a postdoc research fellow at Johns Hopkins Medical School, discusses a non-surgical treatment for post-hemorrhagic hydrocephalus of prematurity (PHHP). PHHP occurs after interventricular hemorrhage (IVH) in premature infants. Surgical intervention outcomes are poor, leading to ongoing morbidity and mortality in parts of the world without access to surgery. Conteh presents a new model using rats to replicate PHHP and proposes that treatment with erythropoietin (EPO) and melatonin can restore motile ependymoma cilia function, preventing hydrocephalus. Their study shows positive outcomes with EPO and melatonin treatment in rat models, suggesting potential for safe and effective therapeutics for PHHP in the future.<br /><br />Transcript credit: YouTube video by Johns Hopkins Medical School.

Asset Caption

Fatu S. Conteh, MD

Keywords

PHHP

EPO

melatonin

rat models

therapeutics