2018 AANS Annual Scientific Meeting-722. Pediatric supratentorial ependymoma: surgical, clinical, and molecular analysis

722. Pediatric supratentorial ependymoma: surgical, clinical, and molecular analysis

Video Transcription

Video Summary

In this video, Jock Lillard, a fourth-year medical student from the University of Tennessee, discusses a study conducted at St. Jude Children's Research Hospital on pediatric supratentorial ependymomas. The study looked at 73 patients and compared various factors including age at diagnosis, tumor grade, extent of tumor resection, and molecular status of the tumors. The results showed that age at diagnosis and tumor grade did not have an impact on progression-free survival or overall survival. However, patients with a RelA fusion showed better outcomes compared to those with a C11 ORF95 gene rearrangement or with no identifiable molecular abnormality. The study suggests the need for further research to understand the reasons behind these findings.

Asset Caption

Jock Lillard

Keywords

pediatric supratentorial ependymomas

molecular status

progression-free survival

overall survival

RelA fusion