2018 AANS Annual Scientific Meeting-Comparison of the Efficacy Two Tranexamic Acid Dosage Regimes for Craniosynostosis Surgery. Multi-center Randomized Controlled Equivalency Trial

Comparison of the Efficacy Two Tranexamic Acid Dosage Regimes for Craniosynostosis Surgery. Multi-center Randomized Controlled Equivalency Trial

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Video Transcription

Video Summary

In this video, Dr. Mark Proctor discusses the use of tranexamic acid (TXA) in craniosynostosis surgery. He mentions that significant blood loss is common in these surgeries, and various techniques have been used to decrease transfusion needs. Dr. Proctor focuses on antifibrinolytics, particularly TXA, which has been shown to be effective in minimizing blood loss and transfusions in previous studies. He presents the results of a randomized blinded study comparing two different dosing regimens of TXA in craniofacial surgery. The study found that a lower dose of TXA is equally effective as a higher dose, suggesting that the higher dose may not be necessary and may increase the risk of dose-related complications.

Asset Caption

Mark R. Proctor, MD, FAANS

Keywords

tranexamic acid

craniosynostosis surgery

blood loss

transfusion needs

antifibrinolytics