2018 AANS Annual Scientific Meeting-Complete 6-Month Primary Endpoint Results from the Prospective INSPIRE Study of the Investigational Neuro-Spinal Scaffold™ in Acute Thoracic Complete Spinal Cord Injury

Complete 6-Month Primary Endpoint Results from the Prospective INSPIRE Study of the Investigational Neuro-Spinal Scaffold™ in Acute Thoracic Complete Spinal Cord Injury

Video Transcription

Video Summary

The video is a presentation on the complete six-month primary endpoint results from the INSPIRE study of the investigational neurospinal scaffold in acute thoracic complete spinal cord injury. The speaker discusses the safety and potential efficacy of the neurospinal scaffold, a device implanted into the spinal cord at the site of injury. Results show that 44% of patients converted from complete to incomplete injuries at six months, surpassing the objective performance criterion of 25%. The study also compared the results to natural history databases and found a higher conversion rate in the INSPIRE group. The FDA has approved a randomized trial called INSPIRE 2.0 to further investigate the scaffold.

Asset Caption

K. Stuart Lee, MD, FAANS, Discussant - Sanjay Dhall, MD, FAANS

Keywords

INSPIRE study

neurospinal scaffold

acute thoracic complete spinal cord injury

conversion rate

INSPIRE 2.0