2018 AANS Annual Scientific Meeting-Deep Brain Stimulation of the Superolateral Medial Forebrain Bundle (sIMFB-DBS) in Depression

Deep Brain Stimulation of the Superolateral Medial Forebrain Bundle (sIMFB-DBS) in Depression

Video Transcription

Video Summary

In this video, Dr. Volker Kohnen discusses supralateral mediophore bundle deep brain stimulation (MFB-DBS) for the treatment of depression. He begins by highlighting the prevalence and impact of depression, noting that current treatment options have limited effectiveness, especially for treatment-resistant depression. He then discusses the various targets that have been explored for DBS in depression and highlights the failure of two pivotal multicenter trials. Dr. Kohnen presents his own research on MFB-DBS, including the rationale behind targeting the mediophore bundle and the results of his studies. He also discusses the potential mechanisms of action and the challenges in study design for DBS in depression. Dr. Kohnen concludes by highlighting the need for further research in this field and the importance of patient selection and optimization of stimulation parameters. This video provides a comprehensive overview of the current state of research on MFB-DBS for depression. No credits are granted in the video.

Asset Caption

Volker Coenen, MD (Germany)

Keywords

MFB-DBS

depression treatment

treatment-resistant depression

DBS targets in depression

study design challenges

patient selection