2023 AANS Annual Scientific Meeting On-Demand-AANS/CNS Section on Tumors Session

Video Transcription

Video Summary

The first video summary discusses endoscopic endonasal surgery as a minimally invasive technique for removing skull base tumors. Preservation of cranial nerves and better postoperative outcomes are emphasized, along with the use of intraoperative ultrasound as a real-time imaging tool. Specific training and online resources are mentioned for learning this technique, with the goal of improving patient outcomes and quality of life.<br /><br />The second summary focuses on research regarding the KL4 gene and its role in the malignant progression of meningioma. The gene acts as a tumor suppressor by regulating the P53 protein, with microRNA and Link RNA playing a role in mediating this effect. The KL4 gene acts differently depending on the type of meningioma, acting as an oncogene in benign cases and a tumor suppressor in malignant cases. The study suggests the potential of the KL4 gene as a therapeutic target for malignant meningioma.<br /><br />The final summary covers a panel discussion on the treatment of cellar lesions, including pituitary tumors and meningiomas. Different surgical approaches and radiation treatment options are discussed, along with the limitations and considerations of each. The management of postoperative complications, such as CSF leaks and hyponatremia, is also addressed, with case studies presented to illustrate the points made. The importance of individualized treatment approaches is emphasized throughout the panel discussion.<br /><br />No specific credits are mentioned in the summaries provided.

Keywords

endoscopic endonasal surgery

skull base tumors

minimally invasive technique

cranial nerves preservation

postoperative outcomes

intraoperative ultrasound

training resources

patient outcomes

quality of life

KL4 gene

malignant progression

meningioma

tumor suppressor

P53 protein regulation

microRNA