49th Annual Meeting of the AANS/CNS Section on Pediatric Neurological Surgery Archive-Hemispherectomy in Children with Epilepsy: A 10 Year Review

Video Transcription

Video Summary

The video presentation is about the work of HEMIS4-Actomic in children with epilepsy, specifically a 15-year review. HEMIS4-Actomic is a surgical procedure that involves the complete removal or functional disconnection of a cerebral HEMIS4 for epilepsy patients. The study analyzed the outcomes of 60 patients who underwent the procedure between 2004 and 2019. The majority of patients were male and Caucasian. Preoperatively, most patients experienced a delay in seizure frequency, and some had undergone previous epilepsy surgeries. The median age of seizure onset was 13 months, and the median age of the first HEMIS4-Actomic surgery was 71 months. Only one stroke complication was clinically significant. Six months post-surgery, 70% of patients were seizure-free. Three patients required a second surgery, including a conversion to an economical procedure and other types of ablation and resection. Logistic regression analysis showed that certain preoperative variables were associated with seizure freedom. The study concluded that HEMIS4-Actomic is a reliable and effective technique, with higher success rates in younger patients, suggesting that early intervention leads to better seizure reduction. The mentors mentioned are Dr. Blanc and Dr. Rizzo.

Keywords

HEMIS4-Actomic

children with epilepsy

surgical procedure

seizure frequency

epilepsy surgeries