AANS Beyond 2021: Full Collection-Neurosurgery In Press Stereotactic & Functional Neurosurgery Update

Neurosurgery In Press Stereotactic & Functional Neurosurgery Update

Video Transcription

Video Summary

In this video, Aviva Yabash, Professor of Neurosurgery and Chairman of the Department of Neurosurgery at the University of Nebraska Medical Center, discusses ongoing clinical trials in stereotactic and functional neurosurgery. Yabash highlights the impact of the COVID-19 pandemic on surgical volume and patient enrollment for clinical trials. She focuses on specific clinical trials for the treatment of Parkinson's disease, epilepsy, dementia, and tinnitus. For Parkinson's disease, Yabash discusses gene therapy trials using adeno-associated environment vectors and AADC enzyme. She also mentions a Phase 1B trial by Voyager Therapeutics using VY-AADC for advanced Parkinson's disease. In terms of epilepsy treatment, Yabash mentions the SLATE trial and provides an overview of responsive neurostimulation (RNS) as a treatment option. She discusses the safety and efficacy of RNS and highlights the potential of using convolutional neural network models to improve diagnostic assessments. Yabash briefly touches on deep brain stimulation (DBS) for dementia and mentions a trial on caudate stimulation for tinnitus. Overall, she emphasizes the need to stay updated on these ongoing clinical trials. No credits were mentioned in the video.

Keywords

Neurosurgery

Clinical trials

Parkinson's disease

Epilepsy treatment

Dementia

Tinnitus