AANS Beyond 2021: Scientific Papers Collection-Serial Connectome Mapping of Domain-General Higher-Order Cognition Cortical Neurosurgery

Serial Connectome Mapping of Domain-General Higher-Order Cognition Cortical Neurosurgery

Video Transcription

Video Summary

The speaker discusses the problem of memory and cognitive issues in patients with brain tumors. They propose using serial connectome mapping to understand the brain's cognitive functions and improve surgical outcomes. Connectomes are brain wiring diagrams that represent the structural and functional connections in the brain. The speaker shares findings from studying healthy individuals and patients undergoing glioma surgery. They find that the frontal parietal network is crucial for cognition and that low-grade gliomas infiltrate this network. Frontal parietal activity decreases immediately after surgery but recalibrates at month 3, suggesting the optimal window for cognitive rehabilitation. Perioperative modularity can predict long-term cognitive trajectories. Ultimately, this research aims to enhance cognitive outcomes after brain surgery. The speaker thanks their supervisors, funding sources, and research team for their contributions.

Keywords

memory

cognitive issues

brain tumors

connectome mapping

surgical outcomes