APP Master Sessions-Multiple Intracranial Aneurysms: Incidence and Risk Factors

Multiple Intracranial Aneurysms: Incidence and Risk Factors

Video Transcription

Video Summary

In this video, Alexandra Santos from the University of Sao Paolo discusses multiple intracranial aneurysms. She begins by thanking WNS and Professor Abelval Figueiredo for their support. Santos explains that 8-30% of patients with intracranial aneurysms have multiple lesions, which can present challenges for neurosurgeons. She discusses a prospective study conducted at a Brazilian institution, which included 1,404 patients with intracranial aneurysms. The study found that multiple aneurysms occurred in 36% of cases, with a higher incidence in females and smokers. Age, female sex, and smoking were identified as risk factors. Santos also explores the association of estrogen levels, oxidative stress, and inflammation with aneurysm development. Arterial hypertension did not significantly influence the incidence of multiple intracranial aneurysms. The study concludes that multiple aneurysms primarily affect women in their sixties and smokers.

Keywords

intracranial aneurysms

neurosurgeons

prospective study

risk factors

estrogen levels