Best of the AANS Session-Discussant Different Principles Govern Multiple Scales of Brain Folding

Discussant Different Principles Govern Multiple Scales of Brain Folding

Video Transcription

Video Summary

The video features Ellen Grant, a pediatric neuroradiologist from Boston Children's Hospital, discussing a paper on volumetric analyses of brain folding. Grant acknowledges her colleagues Ki-Ho Im, Lana Vasan, and Hak-Jin Yun for their assistance. The paper examines differences in folding between various brain regions and concludes that the capillary does not provide mechanical constraints during gyrification. Grant highlights the limitations of the study, such as the inability to capture depth changes accurately and the exclusion of individual variations due to atlases. She emphasizes that gyrification is an important biomarker for health and disease and calls for improved MRI techniques to study individual variations and fetal brain development before 21 weeks gestational age. The video ends with a credit to Aspect Imaging for Grant's position on their Scientific Advisory Board.

Keywords

brain folding

gyrification

MRI techniques

biomarker

fetal brain development