Cavernous Malformations: Management of Difficult Pediatric and Adult Lesions-Edward R. Smith, MD, FAANS Video

Video Transcription

Video Summary

This video is a talk by Ed Smith from Boston Children's Hospital on pediatric cavernous malformations. The talk covers various aspects of cavernous malformations, including what they are, why they are a problem, treatment issues, natural history, and indications for surgery. Cavernous malformations are described as slow-flow vascular malformations that affect a high percentage of the population. The talk discusses the genetic associations and pathophysiology of these malformations. It also explores treatment options, including surgical approaches and advances in technology, such as 3D printing and ultrasound-guided procedures. The talk mentions ongoing research into drug therapies, inflammation modulation, and the role of the microbiome in the development and treatment of cavernous malformations. The speaker emphasizes the need for multidisciplinary approaches and advances in molecular biology to improve outcomes for children with these malformations.

Keywords

pediatric cavernous malformations

slow-flow vascular malformations

genetic associations

pathophysiology

surgical approaches

advances in technology