Cerebral Metastatic Disease-Video

Video Transcription

Video Summary

This video discusses the epidemiology, pathogenesis, and treatment options for metastatic brain tumors. It mentions that there are approximately 300,000 new brain metastases cases in the U.S. each year, accounting for over half of all brain tumors. It explains that brain metastases are often the first sign of systemic cancer and are most commonly derived from lung, breast, melanoma, renal, and gastrointestinal cancers. The distribution of brain metastases in the brain follows blood flow, with most located in the cerebral hemispheres. <br /><br />The video discusses the development of brain metastasis, including the escape of cancer cells from the primary tumor, survival in the bloodstream, and growth in the brain. It explains that treatment options for brain metastases include observation, radiotherapy, radiosurgery, chemotherapy, and surgery. Whole brain radiation therapy is commonly used, but it has limitations and can lead to cognitive decline. The addition of surgery or stereotactic radiosurgery to whole brain radiation therapy has shown improved survival rates in patients with single or multiple brain metastases. <br /><br />The video also mentions the importance of early diagnosis and staging workup, as well as the use of intrathecal chemotherapy for leptomeningeal disease. The American Association of Neurological Surgeons and Congress of Neurological Surgeons have published guidelines for the management of brain metastases, highlighting the benefits of surgery and stereotactic radiosurgery in conjunction with whole brain radiation therapy.<br /><br />No credits were given in the transcript.

Keywords

metastatic brain tumors

brain metastases

treatment options

whole brain radiation therapy

stereotactic radiosurgery

early diagnosis

management of brain metastases