Cerebrovascular Session-Functional Connectivity Deficits After Experimental Subarachnoid Hemorrhage

Functional Connectivity Deficits After Experimental Subarachnoid Hemorrhage

Video Transcription

Video Summary

The video transcript discusses the research conducted by Julian Clark on functional connectivity deficits after experimental subarachnoid hemorrhage (SAH). SAH is a severe injury that often leads to poor patient outcomes and high mortality rates. Clark's research focuses on delayed cerebral ischemia (DCI) as a consequence of SAH and investigates the use of hypoxic post-conditioning as a therapy. Through various experiments and imaging techniques, Clark shows that SAH induces deficits in functional connectivity, but these deficits can be protected against using hypoxic post-conditioning and the activation of SIRT1. The findings suggest that functional connectivity analysis could be a valuable tool in understanding and testing new therapies for SAH patients. Clark acknowledges the mentorship of Dr. Ziffel and thanks everyone involved in the project.

Keywords

functional connectivity deficits

subarachnoid hemorrhage

poor patient outcomes

delayed cerebral ischemia

hypoxic post-conditioning