Front Row On Demand Full Collection-Minimally Invasive Parafascicular Surgery for Deep-Seated Brain Tumors and 5-ALA Fluorescence-Guided Surgery for High-Grade Gliomas

Minimally Invasive Parafascicular Surgery for Deep-Seated Brain Tumors and 5-ALA Fluorescence-Guided Surgery for High-Grade Gliomas

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Video Summary

In this video, the speakers discuss the use of 5-ALA fluorescence-guided surgery for tumor resection. They begin by introducing the use of NeuroU, an online educational website of the AANS, and the Front Row series, which features renowned experts in various topics. The presenters discuss the use of 5-ALA fluorescence-guided surgery for high-grade gliomas and deep-seated brain tumors. They explain how 5-ALA accumulates in tumor cells and allows for real-time image guidance during surgery. The speakers also discuss the diagnostic accuracy of fluorescence visualization and the safety and potential challenges of using this approach. They touch on the limitations of neuropeptidation in visualizing tumor margins and the importance of resecting beyond the contrast-enhancing border. The speakers emphasize the need for new intraoperative visualization technologies and mention the potential for combining fluorescence-guided surgery with photodynamic therapy. They also discuss the current and future applications of 5-ALA fluorescence-guided surgery and the expansion into other types of tumors. Finally, they thank the organizations and individuals who have contributed to the development and approval of 5-ALA for glioma surgery.

Keywords

5-ALA fluorescence-guided surgery

tumor resection

NeuroU

high-grade gliomas

deep-seated brain tumors

real-time image guidance

fluorescence visualization

safety

intraoperative visualization technologies

glioma surgery