Neurosurgery in Press: Latest Results of Clinical Trials in Neurosurgery and Allied Fields-Clinical Trials Updates Vascular

Video Transcription

Video Summary

In this video, Dr. Sepi Amin-Hanjani, a professor at the University of Illinois at Chicago, provides a summary of advances in vascular surgery over the past year. The video covers various topics, including trials updates in the vascular arena, acute ischemic stroke, mobile stroke units, decompressive hemicraniectomy for large hemispheric stroke, stroke prevention, vascular malformations, and aneurysms and subarachnoid hemorrhage. Dr. Amin-Hanjani discusses the results of several studies and meta-analyses in these areas, highlighting key findings and conclusions. Some of the notable findings include the efficacy of mechanical thrombectomy for acute ischemic stroke, the potential benefit of neuroprotectant therapy in thrombectomy patients who don't receive alteplase, the question of whether bridging therapy is necessary for LVO mechanical thrombectomy patients, the positive impact of mobile stroke units on outcomes, the effectiveness of decompressive hemicraniectomy for large hemispheric stroke, the equivalent outcomes of carotid endarterectomy and carotid stenting for asymptomatic carotid disease, the controversy surrounding the ARUBA trial on AVM intervention, the low incidence of dural fistulas after treatment of cerebral venous thrombosis, and the comparable outcomes of clipping and coiling for MCA aneurysms. The video also discusses the ULTRA Early Trial, which assessed the use of tranexamic acid for reducing re-bleeding in subarachnoid hemorrhage patients, and found no significant improvement in clinical outcomes or re-hemorrhage rates. Although the results of these studies and trials may influence current practices and guidelines, further research is needed to provide a clearer understanding of these topics.

Keywords

vascular surgery

acute ischemic stroke

mobile stroke units

decompressive hemicraniectomy

stroke prevention

vascular malformations