Plenary Session Abstracts and Discussant Presentations-Deep Immunophenotyping in Aneurysmal Subarachnoid Hemorrhage: A Prospective and Controlled Exploratory Clinical Study

Deep Immunophenotyping in Aneurysmal Subarachnoid Hemorrhage: A Prospective and Controlled Exploratory Clinical Study - Sajjad Muhammad

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Video Summary

Professor Sajid Muhammad presented a study on immune profiling in subarachnoid hemorrhage, focusing on exploring mechanisms during early brain injury and identifying potential therapeutic targets. The study involved 75 patients, revealing increased monocytes and pro-inflammatory Th17 cells, indicating a systemic pro-inflammatory shift. Anti-inflammatory cell loss correlated with complications such as vasospasm. Discussant Dr. Sander Connolly highlighted the study's strengths and its historical context, while noting limitations like sample size and need for further evidence. Future directions include exploring therapeutic strategies and incorporating advanced genomic techniques for deeper insights.

Keywords

immune profiling

subarachnoid hemorrhage

pro-inflammatory cells

therapeutic targets

genomic techniques