Surgical Advances in Epilepsy Surgery-Surgical Advances in Epilepsy Surgery

Video Transcription

Video Summary

The session featured a series of presentations focused on recent advancements and research in the field of functional neurosurgery and epilepsy treatment. Key highlights included a presentation on the efficacy of anterior temporal lobectomy (ATL) compared to laser ablation in treating temporal lobe epilepsy. The study found that while both methods initially showed comparable seizure outcomes, ATL offered more sustained seizure control over time. Cognitive outcomes showed smaller declines in naming for laser ablation, though both treatments induced long-term memory and naming declines.<br /><br />Another study examined the use of phosphenetoin versus levotiracetam as prophylactic treatments in awake craniotomy procedures. Results indicated that phosphenetoin significantly reduced the risk of composite complications, seizures, and neurological deficits compared to levotiracetam.<br /><br />Furthermore, research on slow gamma oscillations as biomarkers in deep brain stimulation for epilepsy was discussed. Findings from an ongoing clinical trial suggested that targeting and modulating these oscillations could improve seizure outcomes and offered potential pathways for optimizing patient-specific DBS parameters.<br /><br />Additional discussions covered multimodal mapping of brain regions related to reading, highlighting the importance of preserving the visual word form area to maintain reading functions, and describing potential recovery pathways after surgical interventions.<br /><br />The session concluded with a presentation on managing deep brain stimulation emergencies and the role of a well-defined strategy for handling complications such as hardware issues and post-operative neurocognitive side effects. Overall, the session provided diverse insights into innovative research and clinical practices aimed at improving therapeutic outcomes in functional neurosurgery and epilepsy.

Keywords

functional neurosurgery

epilepsy treatment

anterior temporal lobectomy

laser ablation

awake craniotomy

phosphenetoin

levotiracetam

gamma oscillations

deep brain stimulation

multimodal mapping

neurocognitive side effects