AANS Online Scientific Sessions: Tumor-Navigated Repetitive Transcranial Magnetic Stimulation Improves the Outcome of Postsurgical Ischemia-related Paresis in Glioma Patients – A Randomized, Sham-controlled Double-blinded Trial

Navigated Repetitive Transcranial Magnetic Stimulation Improves the Outcome of Postsurgical Ischemia-related Paresis in Glioma Patients – A Randomized, Sham-controlled Double-blinded Trial

Video Transcription

Video Summary

The video summarizes the results of a randomized trial on navigated repetitive transcranial magnetic stimulation (NRTMS) and its impact on post-surgical ischemia-related paresis in glioma patients. NRTMS therapy has previously proven effective in stroke patients, specifically when low-frequency stimulation of the non-damaged hemisphere is used to reduce transcalosal inhibition. In this trial, the objective was to assess the effect of post-operative NRTMS therapy on glioma patients with acute surgery-related paresis of the upper extremity. The trial involved randomized sham-controlled double-blinded groups receiving either NRTMS stimulation or sham stimulation before physical therapy for seven consecutive days. The primary endpoint was the change in Fugl-Meyer assessments, and secondary outcome measures were assessed. The trial showed statistically significant improvements in motor function for patients who received NRTMS stimulation combined with physical therapy. No adverse events were reported.

Asset Subtitle

Sebastian Ille, MD

Keywords

navigated repetitive transcranial magnetic stimulation

post-surgical ischemia-related paresis

glioma patients

NRTMS therapy

Fugl-Meyer assessments