Young Neurosurgeons and Rapid Fire Abstracts-A Functional Circuit for Executive Control

Video Transcription

Video Summary

In this video, David Bonda, a neurosurgery resident, describes his research on executive control and reflexive behavior. He explains how psychiatric disorders are often characterized by dysfunction in executive control and sets out to better understand the neurophysiological and computational aspects of this control using mice as models. Bonda introduces a novel behavioral paradigm involving an LED, a shelter, and an aversive stimulus to test the mice's ability to overcome reflexive behavior and obtain a reward. He presents neuronal tracing and manipulation techniques, as well as physiological data from the medial prefrontal cortex, superior colliculus, and periaqueductal gray, suggesting the importance of these brain regions in executive control. Bonda credits the members of the Kepich Lab and collaborators in the Austin and Bronco Lab, as well as his mentors for their support.

Asset Subtitle

David Bonda, MD

Keywords

executive control

reflexive behavior

mice models

neuronal tracing

physiological data