Young Neurosurgeons and Rapid Fire Abstracts-Osteoconductive Bone Adhesive Versus Plates and Screws for Cranial Flap Fixation in an Ovine Model

Osteoconductive Bone Adhesive Versus Plates and Screws for Cranial Flap Fixation in an Ovine Model

Video Transcription

Video Summary

The video discusses the use of a novel bone adhesive called TTC-PPS for cranial bone flap fixation compared to conventional titanium plates and screws. The study was conducted on female sheep, where bilateral craniotomies were performed, and the bone flaps were secured using TTC-PPS or the experimental bone cement, or with titanium plates and screws as the control group. The bone healing, tissue effects, and remodeling were analyzed using macroscopic observations, histopathology, and biomechanical testing. Results showed that TTC-PPS had better bone flap fixation and healing compared to plates and screws, with minimal fibrosis and soft tissue volume. The adhesive shows promise for human cranial bone flap fixation and cranioplasty.

Asset Subtitle

Kevin T. Foley, MD, FAANS

Keywords

bone adhesive

TTC-PPS

cranial bone flap fixation

titanium plates and screws

bone healing